Post-operative functional neurological symptom disorder after anesthesia

Post-operative functional neurological symptom disorder after anesthesia

Blog Article

A rare manifestation during the post-anesthetic period may include the occurrence of functional neurological symptom disorder (FNSD).FNSD is described as neurological symptoms that are not consistently explained by neurological or medical conditions.We report a case series consisting of six patients who underwent a general anesthetic at a tertiary referral hospital and experienced FNSD in the immediate post-anesthetic period.Life-threatening causes were excluded based on benign physical exam findings and knowledge of past history.Five of six cases manifested with FNSD only in the immediate post-operative setting after exposure to anesthesia, Clothing and never otherwise experienced these symptoms during their normal daily lives.

MEDLINE and Google Scholar were searched through October 2019 using a highly-sensitive search strategy and identified 38 published cases of post-anesthetic FNSD.Meta-analysis of pooled clinical data revealed that a significant proportion of patients were females (86%), reported a history of psychiatric illness (49%), reported a prior history of FNSD (53%), and underwent general anesthesia as the primary anesthetic (93%).The majority of patients were exposed to diagnostic studies (66% received radiographic tests and 52% received electroencephalogram) as well as pharmacologic therapy (57%).While no deaths occurred, many patients had unanticipated admission to the hospital (53%) or to the intensive care unit (25%).These data may help inform the anesthesia literature on presentation, risk factors, and Collections treatment outcomes of FNSD in the context of anesthetic administration.

We contemplate whether anesthetic agents may predispose a vulnerable brain to manifest with involuntary motor and sensory control seen in FNSD.